BindingDB PrimarySearch

Found 7 hits Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2' and Ligand = 'BDBM50300214'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assay				J Med Chem 53: 1056-66 (2010) Article DOI: 10.1021/jm9012328 BindingDB Entry DOI: 10.7270/Q2BP02VN
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Competitive-type inhibition of autotaxin-mediated FS3 hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Noncompetitive inhibition of autotaxin-mediated pNP-TMP hydrolysis by Michaelis-Menton analysis for enzyme-substrate complex				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of autotaxin-mediated pNP-TMP hydrolysis in human MDA-MB-435 cells by amplex red protocol				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of autotaxin-mediated FS3 hydrolysis in human MDA-MB-435 cells by amplex red protocol				Bioorg Med Chem 18: 769-76 (2010) Article DOI: 10.1016/j.bmc.2009.11.056 BindingDB Entry DOI: 10.7270/Q2RR1ZBG
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50300214 (2-(4-((3,5-dichlorophenyl)carbamothioyl)piperazin-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Memphis Curated by ChEMBL					Assay Description Inhibition of human autotaxin isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assay				J Med Chem 53: 1056-66 (2010) Article DOI: 10.1021/jm9012328 BindingDB Entry DOI: 10.7270/Q2BP02VN
The University of Memphis Curated by ChEMBL					More data for this Ligand-Target Pair