Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Egl nine homolog 1' and Ligand = 'BDBM93422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM93422 (PHD Inhibitor, 12{1,1,2}) Show SMILES CC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1ccc2n(C)c(=O)c(C(=O)NCC(O)=O)c(O)c2c1 |r| Show InChI InChI=1S/C38H37N5O8/c1-22(44)41-30(19-24-12-14-26-10-6-7-11-27(26)16-24)36(49)42-29(18-23-8-4-3-5-9-23)35(48)39-20-25-13-15-31-28(17-25)34(47)33(38(51)43(31)2)37(50)40-21-32(45)46/h3-17,29-30,47H,18-21H2,1-2H3,(H,39,48)(H,40,50)(H,41,44)(H,42,49)(H,45,46)/t29-,30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc.					Assay Description PHD1,2,3 activity was measured utilizing homogeneous time-resolved fluroescence energy transfer techology by detecting the trans-4-hydroxylatio of HI...				J Comb Chem 12: 676-86 (2010) Article DOI: 10.1021/cc100073a BindingDB Entry DOI: 10.7270/Q2B27SXP
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