Compile Data Set for Download or QSAR

Found 10 hits Enz. Inhib. hit(s) with Target = 'Endoplasmic reticulum aminopeptidase 1' and Ligand = 'BDBM50076744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research"Demokritos" Curated by ChEMBL					Assay Description Inhibition of human recombinant ERAP1 expressed in baculovirus infected Sf9 cells using L-leucine-7-amido-4-methyl coumarin as substrate after 5 to 1...				J Med Chem 58: 1524-43 (2015) Article DOI: 10.1021/jm501867s BindingDB Entry DOI: 10.7270/Q2Z321B0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysis				Bioorg Med Chem Lett 26: 4122-6 (2016) Article DOI: 10.1016/j.bmcl.2016.06.062 BindingDB Entry DOI: 10.7270/Q2TT4SW1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research Demokritos Curated by ChEMBL					Assay Description Inhibition of human recombinant ERAP1 using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence microplate reader met...				ACS Med Chem Lett 7: 681-5 (2016) Article DOI: 10.1021/acsmedchemlett.6b00084 BindingDB Entry DOI: 10.7270/Q29P3549
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human ERAP1 using L-AMC as substrate incubated for 5 to 10 mins by fluorescence based assay				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128050 BindingDB Entry DOI: 10.7270/Q2445R98
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Scientific Research Demokritos Curated by ChEMBL					Assay Description Inhibition of human recombinant ERAP1 using L-leucine 7-amido-4-methyl coumarin as substrate after 5 to 10 mins by fluorescence microplate reader met...				ACS Med Chem Lett 7: 681-5 (2016) Article DOI: 10.1021/acsmedchemlett.6b00084 BindingDB Entry DOI: 10.7270/Q29P3549
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
National and Kapodistrian University of Athens Curated by ChEMBL					Assay Description Inhibition of ERAP1 (unknown origin) expressed in Hi5 cells by in vitro fluorimetric assay				J Med Chem 59: 9107-9123 (2016) Article DOI: 10.1021/acs.jmedchem.6b01031 BindingDB Entry DOI: 10.7270/Q2PK0JJG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild type ERAP1 (unknown origin) using L-Rho-Succ-FKARKF as substrate preincubated for 15 mins followed by substrate addition and measu...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00235 BindingDB Entry DOI: 10.7270/Q2QJ7N22
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ERAP1 (unknown origin) using L-AMC as substrate				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128050 BindingDB Entry DOI: 10.7270/Q2445R98
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ERAP1 (unknown origin) using L-AMC as substrate				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128050 BindingDB Entry DOI: 10.7270/Q2445R98
					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum aminopeptidase 1 (Homo sapiens (Human))	BDBM50076744 (CHEMBL3416733) Show SMILES CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human ERAP1				Citation and Details Article DOI: 10.1016/j.ejmech.2020.113053 BindingDB Entry DOI: 10.7270/Q29Z98PR
					More data for this Ligand-Target Pair				3D Structure (crystal)