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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151389'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))
BDBM151389
PNG
(US8987314, B195)
Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ccc(O)nc1
Show InChI InChI=1/C17H18N4O6S3/c1-29(24,25)15(16(23)19-6-7-30(18,26)27)17-21-12-8-10(2-4-13(12)28-17)11-3-5-14(22)20-9-11/h2-5,8-9,15H,6-7H2,1H3,(H,19,23)(H,20,22)(H2,18,26,27)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair