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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151416'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))
BDBM151416
PNG
(US8987314, B227)
Show SMILES NC(=O)c1ccc(cc1)-c1ccc2nc(sc2c1)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1/C26H23F3N4O7S3/c27-26(28,29)40-19-8-1-15(2-9-19)14-42(36,37)22(24(35)32-11-12-43(31,38)39)25-33-20-10-7-18(13-21(20)41-25)16-3-5-17(6-4-16)23(30)34/h1-10,13,22H,11-12,14H2,(H2,30,34)(H,32,35)(H2,31,38,39)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.5n/an/an/an/a8.025



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...


US Patent US8987314 (2015)


BindingDB Entry DOI: 10.7270/Q2W094N8
More data for this
Ligand-Target Pair