Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151442'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151442 (US8987314, B253) Show SMILES Cc1nnc(CNC(=O)C(c2nc3ccc(cc3s2)-c2ccc(F)cc2)S(=O)(=O)Cc2ccccc2)o1 Show InChI InChI=1S/C26H21FN4O4S2/c1-16-30-31-23(35-16)14-28-25(32)24(37(33,34)15-17-5-3-2-4-6-17)26-29-21-12-9-19(13-22(21)36-26)18-7-10-20(27)11-8-18/h2-13,24H,14-15H2,1H3,(H,28,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	42.2	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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