Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151496'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151496 (US8987314, B307) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2ccc(cc2s1)-c1ccccc1F)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C20H19F4N3O5S3/c21-14-4-2-1-3-13(14)12-5-6-15-16(11-12)33-19(27-15)17(18(28)26-8-10-35(25,31)32)34(29,30)9-7-20(22,23)24/h1-6,11,17H,7-10H2,(H,26,28)(H2,25,31,32)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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