Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151498 (US8987314, B309) Show SMILES NS(=O)(=O)CCNC(=O)C(c1nc2cc(ccc2s1)-c1ccc(F)nc1)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C24H20F4N4O6S3/c25-20-8-4-16(12-31-20)15-3-7-19-18(11-15)32-23(39-19)21(22(33)30-9-10-41(29,36)37)40(34,35)13-14-1-5-17(6-2-14)38-24(26,27)28/h1-8,11-12,21H,9-10,13H2,(H,30,33)(H2,29,36,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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