Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151514'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151514 (US8987314, B325) Show SMILES Cc1cc2nc(sc2cc1-c1ccc(cc1)C(O)=O)C(C(=O)NCCS(N)(=O)=O)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H25N3O7S3/c1-16-13-21-22(14-20(16)18-7-9-19(10-8-18)26(31)32)37-25(29-21)23(24(30)28-11-12-39(27,35)36)38(33,34)15-17-5-3-2-4-6-17/h2-10,13-14,23H,11-12,15H2,1H3,(H,28,30)(H,31,32)(H2,27,35,36)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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