Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM151563'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM151563 (US8987314, B374) Show SMILES CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2cc(ccc2s1)-c1ncccn1 Show InChI InChI=1S/C16H17N5O5S3/c1-28(23,24)13(15(22)20-7-8-29(17,25)26)16-21-11-9-10(3-4-12(11)27-16)14-18-5-2-6-19-14/h2-6,9,13H,7-8H2,1H3,(H,20,22)(H2,17,25,26)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	8.0	25
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US8987314 (2015) BindingDB Entry DOI: 10.7270/Q2W094N8
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