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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM318970'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM318970
PNG
(US10173991, Example 11 | benzyl N-(4-{2- [(cyclopr...)
Show SMILES Fc1cc2sc(nc2cc1-c1ccc(NC(=O)OCc2ccccc2)cc1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C31H29FN4O6S2/c32-24-15-26-25(14-23(24)19-6-8-21(9-7-19)35-31(39)42-17-18-4-2-1-3-5-18)36-30(43-26)28(44(40,41)22-12-13-22)29(38)33-16-27(37)34-20-10-11-20/h1-9,14-15,20,22,28H,10-13,16-17H2,(H,33,38)(H,34,37)(H,35,39)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...

US Patent US10173991 (2019)


BindingDB Entry DOI: 10.7270/Q2N018M8
More data for this
Ligand-Target Pair