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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319007'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM319007
PNG
(US10173991, Example 48 | benzyl N-{4-[2- ({[(cyclo...)
Show SMILES CCCCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(F)c(cc2s1)-c1ccc(NC(=O)OCc2ccccc2)cc1
Show InChI InChI=1S/C33H35FN4O6S2/c1-2-3-7-16-46(42,43)30(31(40)35-19-29(39)36-23-14-15-23)32-38-27-18-26(34)25(17-28(27)45-32)22-10-12-24(13-11-22)37-33(41)44-20-21-8-5-4-6-9-21/h4-6,8-13,17-18,23,30H,2-3,7,14-16,19-20H2,1H3,(H,35,40)(H,36,39)(H,37,41)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...

US Patent US10173991 (2019)


BindingDB Entry DOI: 10.7270/Q2N018M8
More data for this
Ligand-Target Pair