Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319094'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319094 (N-[(cyclopropyl- carbamoyl) methyl]-2-{5- fluoro-6...) Show SMILES Fc1cc2nc(sc2cc1-c1cccc(c1)-n1cccn1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)CCC(F)(F)F Show InChI InChI=1S/C26H23F4N5O4S2/c27-19-13-20-21(12-18(19)15-3-1-4-17(11-15)35-9-2-8-32-35)40-25(34-20)23(41(38,39)10-7-26(28,29)30)24(37)31-14-22(36)33-16-5-6-16/h1-4,8-9,11-13,16,23H,5-7,10,14H2,(H,31,37)(H,33,36)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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