Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319205 (N-[(cyclopropyl- carbamoyl) methyl]-2-[5- fluoro-6...) Show SMILES Cc1nc2cc(ccc2s1)-c1cc2sc(nc2cc1F)C(C(=O)NCC(=O)NC1CC1)S(C)(=O)=O Show InChI InChI=1S/C23H21FN4O4S3/c1-11-26-16-7-12(3-6-18(16)33-11)14-8-19-17(9-15(14)24)28-23(34-19)21(35(2,31)32)22(30)25-10-20(29)27-13-4-5-13/h3,6-9,13,21H,4-5,10H2,1-2H3,(H,25,30)(H,27,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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