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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319442'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM319442
PNG
(N-[(cyclopropyl- carbamoyl) methyl]-2- (dimethyl- ...)
Show SMILES CN(C)S(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2c(F)cc(cc2s1)-c1ccc2c(ccn(C)c2=O)c1
Show InChI InChI=1S/C26H26FN5O5S2/c1-31(2)39(36,37)23(24(34)28-13-21(33)29-17-5-6-17)25-30-22-19(27)11-16(12-20(22)38-25)14-4-7-18-15(10-14)8-9-32(3)26(18)35/h4,7-12,17,23H,5-6,13H2,1-3H3,(H,28,34)(H,29,33)
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 1n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...

US Patent US10173991 (2019)


BindingDB Entry DOI: 10.7270/Q2N018M8
More data for this
Ligand-Target Pair