Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319515'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319515 (4-[2- ({[(cyclopropyl- carbamoyl)methyl] carbamoyl...) Show SMILES CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(F)c(cc2s1)-c1ccc(cc1)C(=O)NCCc1ccccc1 Show InChI InChI=1S/C30H29FN4O5S2/c1-42(39,40)27(29(38)33-17-26(36)34-21-11-12-21)30-35-24-16-23(31)22(15-25(24)41-30)19-7-9-20(10-8-19)28(37)32-14-13-18-5-3-2-4-6-18/h2-10,15-16,21,27H,11-14,17H2,1H3,(H,32,37)(H,33,38)(H,34,36)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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