Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelial lipase' and Ligand = 'BDBM319525'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM319525 (5-amino-1-{4-[2- ({[(cyclopropyl- carbamoyl)methyl...) Show SMILES COCCS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(F)c(cc2s1)-c1ccc(cc1)-n1ncc(C(N)=O)c1N Show InChI InChI=1S/C27H28FN7O6S2/c1-41-8-9-43(39,40)23(26(38)31-13-22(36)33-15-4-5-15)27-34-20-11-19(28)17(10-21(20)42-27)14-2-6-16(7-3-14)35-24(29)18(12-32-35)25(30)37/h2-3,6-7,10-12,15,23H,4-5,8-9,13,29H2,1H3,(H2,30,37)(H,31,38)(H,33,36)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...				US Patent US10173991 (2019) BindingDB Entry DOI: 10.7270/Q2N018M8
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