Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Endothelin-1 receptor (Homo sapiens (Human)) | BDBM50050047 (2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory activity was evaluated against human Endothelin A receptor | J Med Chem 39: 982-91 (1996) Article DOI: 10.1021/jm9505932 BindingDB Entry DOI: 10.7270/Q2DB80WG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Endothelin-1 receptor (RAT) | BDBM50050047 (2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenates | J Med Chem 39: 968-81 (1996) Article DOI: 10.1021/jm950592+ BindingDB Entry DOI: 10.7270/Q2J38RMT | |||||||||||
More data for this Ligand-Target Pair |