Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50230173'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50230173 (CHEMBL4101918) Show SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc5OCOc5c4)cc3)c12 Show InChI InChI=1S/C25H21N5O4/c26-22-21-17(2-1-3-18(21)29-30-22)14-4-6-15(7-5-14)27-23(31)25(10-11-25)24(32)28-16-8-9-19-20(12-16)34-13-33-19/h1-9,12H,10-11,13H2,(H,27,31)(H,28,32)(H3,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assay				Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27
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