Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50230177'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50230177 (CHEMBL4071731) Show SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(OC(F)(F)F)cc4Br)cc3)c12 Show InChI InChI=1S/C25H19BrF3N5O3/c26-17-12-15(37-25(27,28)29)8-9-18(17)32-23(36)24(10-11-24)22(35)31-14-6-4-13(5-7-14)16-2-1-3-19-20(16)21(30)34-33-19/h1-9,12H,10-11H2,(H,31,35)(H,32,36)(H3,30,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assay				Eur J Med Chem 127: 275-285 (2017) Article DOI: 10.1016/j.ejmech.2016.12.059 BindingDB Entry DOI: 10.7270/Q2XW4N27
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