Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 4' and Ligand = 'BDBM50340561'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340561 (4-(3-(4-((5-(hydroxymethyl)-2-methylphenyl)(methyl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCN(O)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H35N7O3/c1-20-3-4-21(19-35)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-9-34(36)10-8-32)18-24(17-22)33-11-13-37-14-12-33/h3-6,15-18,35-36H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EPHB4				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50340561 (4-(3-(4-((5-(hydroxymethyl)-2-methylphenyl)(methyl...) Show SMILES CN(c1ccnc(Nc2cc(cc(c2)N2CCN(O)CC2)N2CCOCC2)n1)c1cc(CO)ccc1C Show InChI InChI=1S/C27H35N7O3/c1-20-3-4-21(19-35)15-25(20)31(2)26-5-6-28-27(30-26)29-22-16-23(32-7-9-34(36)10-8-32)18-24(17-22)33-11-13-37-14-12-33/h3-6,15-18,35-36H,7-14,19H2,1-2H3,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibition of human EphB4 autophosphorylation expressed in CHOK1 cells				Bioorg Med Chem Lett 21: 2207-11 (2011) Article DOI: 10.1016/j.bmcl.2011.03.009 BindingDB Entry DOI: 10.7270/Q2PK0GGR
					More data for this Ligand-Target Pair