Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM270586'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270586 ((S)-N6- (benzo[d]thiazol-7- yl(1-(1- (trifluoromet...) Show SMILES CC(C)(C)CNc1ncnc2c(Br)cc(N[C@H](c3cn(nn3)C3(CC3)C(F)(F)F)c3cccc4ncsc34)cc12 |r| Show InChI InChI=1S/C27H26BrF3N8S/c1-25(2,3)12-32-24-17-9-15(10-18(28)21(17)33-13-34-24)36-22(16-5-4-6-19-23(16)40-14-35-19)20-11-39(38-37-20)26(7-8-26)27(29,30)31/h4-6,9-11,13-14,22,36H,7-8,12H2,1-3H3,(H,32,33,34)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	195	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair