Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM270592'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	11.3	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270592 ((S)-6-(((1-(1- (difluoromethyl) cyclopropyl)-1H-1,...) Show SMILES Cn1ccc2c(cccc2c1=O)[C@H](Nc1cc(C#N)c2ncnc(NCC(C)(C)C)c2c1)c1cn(nn1)C1(CC1)C(F)F |r| Show InChI InChI=1S/C31H31F2N9O/c1-30(2,3)16-35-27-23-13-19(12-18(14-34)25(23)36-17-37-27)38-26(24-15-42(40-39-24)31(9-10-31)29(32)33)21-6-5-7-22-20(21)8-11-41(4)28(22)43/h5-8,11-13,15,17,26,29,38H,9-10,16H2,1-4H3,(H,35,36,37)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	11.3	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair