Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM270602'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270602 ((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...) Show SMILES Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl |r| Show InChI InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	318	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270602 ((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...) Show SMILES Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl |r| Show InChI InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	318	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270602 ((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...) Show SMILES Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl |r| Show InChI InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270602 ((S)-N4-(3-chloro-4- fluorophenyl)-N6- ((4-chloroph...) Show SMILES Fc1ccc(Nc2ncnc3ccc(N[C@H](c4cn(nn4)C4CCN(CC4)C4COC4)c4ccc(Cl)cc4)cc23)cc1Cl |r| Show InChI InChI=1S/C31H29Cl2FN8O/c32-20-3-1-19(2-4-20)30(29-15-42(40-39-29)23-9-11-41(12-10-23)24-16-43-17-24)37-21-6-8-28-25(13-21)31(36-18-35-28)38-22-5-7-27(34)26(33)14-22/h1-8,13-15,18,23-24,30,37H,9-12,16-17H2,(H,35,36,38)/t30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair