Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM270604'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10577352 (2020) BindingDB Entry DOI: 10.7270/Q20P12D3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM270604 ((S)-8-chloro-N4-(3- chloro-4- fluorophenyl)-N6- ((...) Show SMILES CCN1CCC(CC1)n1cc(nn1)[C@@H](Nc1cc(Cl)c2ncnc(Nc3ccc(F)c(Cl)c3)c2c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C30H28Cl3FN8/c1-2-41-11-9-22(10-12-41)42-16-27(39-40-42)28(18-3-5-19(31)6-4-18)37-21-13-23-29(25(33)15-21)35-17-36-30(23)38-20-7-8-26(34)24(32)14-20/h3-8,13-17,22,28,37H,2,9-12H2,1H3,(H,35,36,38)/t28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	527	n/a	n/a	7.0	25
GILEAD SCIENCES, INC. US Patent					Assay Description EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...				US Patent US10059695 (2018) BindingDB Entry DOI: 10.7270/Q2FB54Z6
					More data for this Ligand-Target Pair