Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50142030'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50142030 (CHEMBL3758830) Show SMILES Cn1nc(Nc2nc(nc3c2COC3(C)C)-c2cn[nH]c2)c2cccc(F)c12 Show InChI InChI=1S/C19H18FN7O/c1-19(2)15-12(9-28-19)17(24-16(23-15)10-7-21-22-8-10)25-18-11-5-4-6-13(20)14(11)27(3)26-18/h4-8H,9H2,1-3H3,(H,21,22)(H,23,24,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin)				Bioorg Med Chem Lett 26: 534-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.078 BindingDB Entry DOI: 10.7270/Q2HH6MZQ
					More data for this Ligand-Target Pair