Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50144590'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50144590 (CHEMBL3759015) Show SMILES COc1cc2c(Nc3ccc(NC(=O)c4cccc(Cl)c4)cc3)ncnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C29H30ClN5O4/c1-37-26-17-24-25(18-27(26)39-13-3-10-35-11-14-38-15-12-35)31-19-32-28(24)33-22-6-8-23(9-7-22)34-29(36)20-4-2-5-21(30)16-20/h2,4-9,16-19H,3,10-15H2,1H3,(H,34,36)(H,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human EGFR preincubated for 10 mins followed by addition of FAM-labeled peptide and incubated for 10 mins by Caliper motility shift ass...				Eur J Med Chem 109: 371-9 (2016) Article DOI: 10.1016/j.ejmech.2015.12.032 BindingDB Entry DOI: 10.7270/Q2M32XKS
					More data for this Ligand-Target Pair