Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50171516'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171516 (CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...) Show SMILES Fc1cc(Cl)c(Cl)cc1Nc1ncnc2ccc(NC(=O)C=C)cc12 Show InChI InChI=1S/C17H11Cl2FN4O/c1-2-16(25)23-9-3-4-14-10(5-9)17(22-8-21-14)24-15-7-12(19)11(18)6-13(15)20/h2-8H,1H2,(H,23,25)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171516 (CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...) Show SMILES Fc1cc(Cl)c(Cl)cc1Nc1ncnc2ccc(NC(=O)C=C)cc12 Show InChI InChI=1S/C17H11Cl2FN4O/c1-2-16(25)23-9-3-4-14-10(5-9)17(22-8-21-14)24-15-7-12(19)11(18)6-13(15)20/h2-8H,1H2,(H,23,25)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nM				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171516 (CHEMBL363815 | N-[4-(4,5-Dichloro-2-fluoro-phenyla...) Show SMILES Fc1cc(Cl)c(Cl)cc1Nc1ncnc2ccc(NC(=O)C=C)cc12 Show InChI InChI=1S/C17H11Cl2FN4O/c1-2-16(25)23-9-3-4-14-10(5-9)17(22-8-21-14)24-15-7-12(19)11(18)6-13(15)20/h2-8H,1H2,(H,23,25)(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 6.7-20 nM				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair