Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Hadassah Hebrew University Curated by ChEMBL | Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate | J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hadassah Hebrew University Curated by ChEMBL | Assay Description Inhibition of HER1 kinase in intact DHER14 cells | J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Hadassah Hebrew University Curated by ChEMBL | Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 4-10 nM | J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50171520 ((E)-4-Dimethylamino-but-2-enoic acid [4-(4,5-dichl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Hadassah Hebrew University Curated by ChEMBL | Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 10-50 nM | J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3 | |||||||||||
More data for this Ligand-Target Pair |