Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50171525'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171525 (2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...) Show SMILES ClCC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1 Show InChI InChI=1S/C16H12ClIN4O/c17-8-15(23)21-12-4-5-14-13(7-12)16(20-9-19-14)22-11-3-1-2-10(18)6-11/h1-7,9H,8H2,(H,21,23)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171525 (2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...) Show SMILES ClCC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1 Show InChI InChI=1S/C16H12ClIN4O/c17-8-15(23)21-12-4-5-14-13(7-12)16(20-9-19-14)22-11-3-1-2-10(18)6-11/h1-7,9H,8H2,(H,21,23)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 4-10 nM				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50171525 (2-Chloro-N-[4-(3-iodo-phenylamino)-quinazolin-6-yl...) Show SMILES ClCC(=O)Nc1ccc2ncnc(Nc3cccc(I)c3)c2c1 Show InChI InChI=1S/C16H12ClIN4O/c17-8-15(23)21-12-4-5-14-13(7-12)16(20-9-19-14)22-11-3-1-2-10(18)6-11/h1-7,9H,8H2,(H,21,23)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Hadassah Hebrew University Curated by ChEMBL					Assay Description Inhibition of EGF Receptor autophosphorylation in A431 cell lysate				J Med Chem 48: 5337-48 (2005) Article DOI: 10.1021/jm0580196 BindingDB Entry DOI: 10.7270/Q28S4PG3
					More data for this Ligand-Target Pair