Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50177862'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50177862 (CHEMBL3814572) Show SMILES CN(C(=O)C=C)c1cccc(c1)-n1c(nc2ccccc12)-c1nc(cnc1N)-c1cnn(c1)C1CCN(C)CC1 Show InChI InChI=1S/C30H31N9O/c1-4-27(40)37(3)22-8-7-9-23(16-22)39-26-11-6-5-10-24(26)35-30(39)28-29(31)32-18-25(34-28)20-17-33-38(19-20)21-12-14-36(2)15-13-21/h4-11,16-19,21H,1,12-15H2,2-3H3,(H2,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of wild-type EGFR autophosphorylation in human LoVo cells incubated for 2 hrs followed by EGF-stiumlation for 10 mins by ELISA				ACS Med Chem Lett 7: 514-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00058 BindingDB Entry DOI: 10.7270/Q2474CSN
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50177862 (CHEMBL3814572) Show SMILES CN(C(=O)C=C)c1cccc(c1)-n1c(nc2ccccc12)-c1nc(cnc1N)-c1cnn(c1)C1CCN(C)CC1 Show InChI InChI=1S/C30H31N9O/c1-4-27(40)37(3)22-8-7-9-23(16-22)39-26-11-6-5-10-24(26)35-30(39)28-29(31)32-18-25(34-28)20-17-33-38(19-20)21-12-14-36(2)15-13-21/h4-11,16-19,21H,1,12-15H2,2-3H3,(H2,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R double mutant autophosphorylation in human NCI-H1975 cells incubated for 2 hrs by ELISA				ACS Med Chem Lett 7: 514-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00058 BindingDB Entry DOI: 10.7270/Q2474CSN
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50177862 (CHEMBL3814572) Show SMILES CN(C(=O)C=C)c1cccc(c1)-n1c(nc2ccccc12)-c1nc(cnc1N)-c1cnn(c1)C1CCN(C)CC1 Show InChI InChI=1S/C30H31N9O/c1-4-27(40)37(3)22-8-7-9-23(16-22)39-26-11-6-5-10-24(26)35-30(39)28-29(31)32-18-25(34-28)20-17-33-38(19-20)21-12-14-36(2)15-13-21/h4-11,16-19,21H,1,12-15H2,2-3H3,(H2,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of EGFR exon19 deletion activating mutant autophosphorylation in human PC9 cells incubated for 2 hrs by ELISA				ACS Med Chem Lett 7: 514-9 (2016) Article DOI: 10.1021/acsmedchemlett.6b00058 BindingDB Entry DOI: 10.7270/Q2474CSN
					More data for this Ligand-Target Pair