Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50271906 (2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of EGFR (unknown origin) expressed in human tumor cells | Bioorg Med Chem 16: 5514-28 (2008) Article DOI: 10.1016/j.bmc.2008.04.019 BindingDB Entry DOI: 10.7270/Q2GF0T9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50271906 (2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of EGFR expressed in human A431 cells | Bioorg Med Chem 18: 5261-73 (2010) Article DOI: 10.1016/j.bmc.2010.05.049 BindingDB Entry DOI: 10.7270/Q29Z95W6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50271906 (2-benzyl-N4-(3-bromophenyl)-1H-indole-4,6-diamine ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University Curated by ChEMBL | Assay Description Inhibition of EGFR | Bioorg Med Chem 20: 2444-54 (2012) Article DOI: 10.1016/j.bmc.2012.01.029 BindingDB Entry DOI: 10.7270/Q2XK8G14 | |||||||||||
More data for this Ligand-Target Pair |