Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50429669'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50429669 (CHEMBL2335018) Show SMILES CC(C)(C)C(=O)Nc1nc(Nc2cccc(c2)C(F)(F)F)c2cc(CCc3ccccn3)[nH]c2n1 Show InChI InChI=1S/C25H25F3N6O/c1-24(2,3)22(35)34-23-32-20(30-17-9-6-7-15(13-17)25(26,27)28)19-14-18(31-21(19)33-23)11-10-16-8-4-5-12-29-16/h4-9,12-14H,10-11H2,1-3H3,(H3,30,31,32,33,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGF-induced EGFR phosphorylation in human A431 cells overexpressing EGFR pretreated for 60 mins prior to EGF addition measured after 10...				Bioorg Med Chem 21: 1312-23 (2013) Article DOI: 10.1016/j.bmc.2012.12.045 BindingDB Entry DOI: 10.7270/Q25140KN
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