Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50429670'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50429670 (CHEMBL2335016) Show SMILES CC(C)(C)C(=O)Nc1nc(Nc2ccc(F)c(Cl)c2)c2cc(CCc3ccccn3)[nH]c2n1 Show InChI InChI=1S/C24H24ClFN6O/c1-24(2,3)22(33)32-23-30-20-17(12-15(28-20)8-7-14-6-4-5-11-27-14)21(31-23)29-16-9-10-19(26)18(25)13-16/h4-6,9-13H,7-8H2,1-3H3,(H3,28,29,30,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGF-induced EGFR phosphorylation in human A431 cells overexpressing EGFR pretreated for 60 mins prior to EGF addition measured after 10...				Bioorg Med Chem 21: 1312-23 (2013) Article DOI: 10.1016/j.bmc.2012.12.045 BindingDB Entry DOI: 10.7270/Q25140KN
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