Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM5125'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM5125 (5-{[(5Z)-4-[(3-chloro-4-fluorophenyl)amino]-6-oxo-...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ncnc(Nc4ccc(F)c(Cl)c4)c23)c1C Show InChI InChI=1S/C26H29ClFN7O2/c1-5-35(6-2)10-9-29-26(37)21-14(3)20(32-15(21)4)12-17-22-23(30-13-31-24(22)34-25(17)36)33-16-7-8-19(28)18(27)11-16/h7-8,11-13,32H,5-6,9-10H2,1-4H3,(H,29,37)(H2,30,31,33,34,36)/b17-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
SUGEN, Inc.					Assay Description IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...				Bioorg Med Chem Lett 12: 2153-7 (2002) Article DOI: 10.1016/s0960-894x(02)00364-5 BindingDB Entry DOI: 10.7270/Q200009N
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