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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM5147'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM5147
PNG
((5Z)-5-{[3-methyl-5-(morpholin-4-ylcarbonyl)-1H-py...)
Show SMILES Cc1cc([nH]c1\C=C1/C(=O)Nc2ncnc(N3CCCCC3)c12)C(=O)N1CCOCC1
Show InChI InChI=1S/C22H26N6O3/c1-14-11-17(22(30)28-7-9-31-10-8-28)25-16(14)12-15-18-19(26-21(15)29)23-13-24-20(18)27-5-3-2-4-6-27/h11-13,25H,2-10H2,1H3,(H,23,24,26,29)/b15-12-
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KEGG

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Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



SUGEN, Inc.



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of EGF-R or PDGFR-beta kinase autophosphorylation activity. The assay was performed in 96-well...

Bioorg Med Chem Lett 12: 2153-7 (2002)


Article DOI: 10.1016/s0960-894x(02)00364-5
BindingDB Entry DOI: 10.7270/Q200009N
More data for this
Ligand-Target Pair