BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM23451'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against human estrogen receptor alpha in competitive binding assay				Bioorg Med Chem Lett 14: 1417-21 (2004) Article DOI: 10.1016/j.bmcl.2004.01.031 BindingDB Entry DOI: 10.7270/Q28G8K4S
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	75.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor Alpha				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	75.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Binding affinity for human Estrogen receptor Alpha				J Med Chem 48: 3463-6 (2005) Article DOI: 10.1021/jm0490538 BindingDB Entry DOI: 10.7270/Q2WS8V00
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM23451 (5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^{2,7}....) Show SMILES Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	75.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California US Patent					Assay Description The binding affinity and selectivity of candidate molecules yielded from database screening were determined by a fluorescent polarization competiti...				US Patent US8552057 (2013) BindingDB Entry DOI: 10.7270/Q2CZ35TN
University of Southern California US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)