BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Eukaryotic elongation factor 2 kinase' and Ligand = 'BDBM50053584'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description ATP competitive inhibition of human eEF-2K using 5 uM ATP				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
The University of Texas at Austin Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of eEF2K (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112505 BindingDB Entry DOI: 10.7270/Q2M90D99
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas at Austin Curated by ChEMBL					Assay Description Inhibition of human recombinant eEF-2K expressed in bacteria pre-incubated for 30 mins before adding peptide substrate and [gamma32P]ATP by scintilla...				Bioorg Med Chem 22: 4910-6 (2014) Article DOI: 10.1016/j.bmc.2014.06.050 BindingDB Entry DOI: 10.7270/Q2XD139S
The University of Texas at Austin Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128759 BindingDB Entry DOI: 10.7270/Q26114D7
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Eukaryotic elongation factor 2 kinase (Homo sapiens (Human))	BDBM50053584 (CHEMBL1977874) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of eEF2K (unknown origin) using peptide MH-1 as substrate after 2 hrs by ADP-Glo luminescent assay				Eur J Med Chem 143: 402-418 (2018) Article DOI: 10.1016/j.ejmech.2017.11.065 BindingDB Entry DOI: 10.7270/Q28C9ZS6
Sichuan University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)