Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 2-alpha kinase 1' and Ligand = 'BDBM50414881'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414881 (CHEMBL575913) Show SMILES COc1ccc-2c(Cc3c(NCc4c(C)cccc4Cl)[nH]nc-23)c1 Show InChI InChI=1S/C19H18ClN3O/c1-11-4-3-5-17(20)16(11)10-21-19-15-9-12-8-13(24-2)6-7-14(12)18(15)22-23-19/h3-8H,9-10H2,1-2H3,(H2,21,22,23)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
					More data for this Ligand-Target Pair