Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 2-alpha kinase 1' and Ligand = 'BDBM50414892'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 2-alpha kinase 1 (Homo sapiens (Human))	BDBM50414892 (CHEMBL576168) Show SMILES COc1cc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2cc1OC Show InChI InChI=1S/C20H20ClN3O2/c1-11-5-4-6-16(21)15(11)10-22-20-14-7-12-8-17(25-2)18(26-3)9-13(12)19(14)23-24-20/h4-6,8-9H,7,10H2,1-3H3,(H2,22,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human HRI kinase				Bioorg Med Chem Lett 19: 6548-51 (2009) Article DOI: 10.1016/j.bmcl.2009.10.033 BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
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