Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Exportin-1 (Homo sapiens (Human)) | BDBM50303499 (7-(methyloxy)-2H-chromen-2-one | 7-Methoxycoumarin...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Osaka University Curated by ChEMBL | Assay Description Inhibition of CRM1-mediated hemagglutinin-tagged HIV1 Rev protein nuclear export in human HeLa cells assessed as nucleus localization after 12 hrs by... | Bioorg Med Chem Lett 20: 3717-20 (2010) Article DOI: 10.1016/j.bmcl.2010.04.081 BindingDB Entry DOI: 10.7270/Q21G0MF1 | |||||||||||
More data for this Ligand-Target Pair |