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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Farnesyl diphosphate synthase' and Ligand = 'BDBM50225995'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Farnesyl diphosphate synthase


(Homo sapiens (Human))
BDBM50225995
PNG
(1-chloro-2-(3-pyridinyl)-ethylidene-1,1-bisphospho...)
Show SMILES OP(O)(=O)C(Cl)(Cc1cccnc1)P(O)(O)=O
Show InChI InChI=1S/C7H10ClNO6P2/c8-7(16(10,11)12,17(13,14)15)4-6-2-1-3-9-5-6/h1-3,5H,4H2,(H2,10,11,12)(H2,13,14,15)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 94.6n/an/an/an/an/an/a



University of Southern California

Curated by ChEMBL


Assay Description
Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)


J Med Chem 50: 5967-75 (2007)


Article DOI: 10.1021/jm0702884
BindingDB Entry DOI: 10.7270/Q27944DF
More data for this
Ligand-Target Pair