BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50069269'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH assessed as conversion [14]C-oleamide to oleic acid by Scintillation counting at pH 9				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	9.0	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Concentration of the compound required to inhibit fatty acid amide hydrolase (FAAH) at pH 7.0				Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
The Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Catholique de Louvain Curated by ChEMBL					Assay Description Irreversible inhibition of fatty acid amide hydrolase				J Med Chem 48: 5059-87 (2005) Article DOI: 10.1021/jm058183t BindingDB Entry DOI: 10.7270/Q2J96753
Universit£ Catholique de Louvain Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	9.0	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Inhibitory concentration against Fatty-acid amide hydrolase (FAAH) at pH 9.0				Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50069269 ((R)-octan-2-yl 4-bromo-3-oxobutanoate \| 4-Bromo-3-...) Show SMILES CCCCCC[C@@H](C)OC(=O)CC(=O)CBr Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	7.0	n/a
Institute for Chemical Biology Curated by ChEMBL					Assay Description Compound was tested for inhibitory potency against Fatty-acid amide hydrolase (FAAH) at pH 9.0				Bioorg Med Chem Lett 8: 613-8 (1999) BindingDB Entry DOI: 10.7270/Q2HH6J61
Institute for Chemical Biology Curated by ChEMBL					More data for this Ligand-Target Pair