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Found 2 hits Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50261710'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50261710
PNG
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
Show SMILES O=C(CCCCCCc1ccccc1)c1nnn(n1)-c1ccccn1
Show InChI InChI=1S/C19H21N5O/c25-17(13-7-2-1-4-10-16-11-5-3-6-12-16)19-21-23-24(22-19)18-14-8-9-15-20-18/h3,5-6,8-9,11-12,14-15H,1-2,4,7,10,13H2
PDB

UniProtKB/SwissProt

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PC sid
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Article
PubMed
1.10n/an/an/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of FAAH


J Med Chem 51: 7327-43 (2009)


Article DOI: 10.1021/jm800311k
BindingDB Entry DOI: 10.7270/Q2J67HT8
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50261710
PNG
(7-Phenyl-1-(2-(pyridin-2-yl)-2H-tetrazol-5-yl)-hep...)
Show SMILES O=C(CCCCCCc1ccccc1)c1nnn(n1)-c1ccccn1
Show InChI InChI=1S/C19H21N5O/c25-17(13-7-2-1-4-10-16-11-5-3-6-12-16)19-21-23-24(22-19)18-14-8-9-15-20-18/h3,5-6,8-9,11-12,14-15H,1-2,4,7,10,13H2
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
5.5n/an/an/an/an/an/an/an/a



Institute for Chemical Biology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant FAAH expressed in african green monkey COS7 cells


J Med Chem 51: 4392-403 (2008)


Article DOI: 10.1021/jm800136b
BindingDB Entry DOI: 10.7270/Q26D5TW3
More data for this
Ligand-Target Pair