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Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50339876'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))		BDBM50339876
PNG
(6-bromo-N-(2-fluorophenyl)-4H-spiro[benzo[d][1,3]d...)
Show SMILES Fc1ccccc1NC(=O)N1CCC2(CC1)OCc1cc(Br)ccc1O2
Show InChI InChI=1S/C19H18BrFN2O3/c20-14-5-6-17-13(11-14)12-25-19(26-17)7-9-23(10-8-19)18(24)22-16-4-2-1-3-15(16)21/h1-6,11H,7-10,12H2,(H,22,24)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarin

Bioorg Med Chem Lett 21: 2492-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.052
BindingDB Entry DOI: 10.7270/Q2BG2P9M
More data for this
Ligand-Target Pair