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Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty-acid amide hydrolase 1' and Ligand = 'BDBM50342098'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50342098
PNG
(CHEMBL1765864 | rac-6-[2-(5-Phenylindane-2-carbony...)
Show SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)C1Cc2ccc(cc2C1)-c1ccccc1
Show InChI InChI=1S/C25H18N2O4/c28-23(24-26-14-22(31-24)20-7-4-8-21(27-20)25(29)30)19-12-17-10-9-16(11-18(17)13-19)15-5-2-1-3-6-15/h1-11,14,19H,12-13H2,(H,29,30)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
57n/an/an/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion


J Med Chem 54: 2805-22 (2011)


Article DOI: 10.1021/jm101597x
BindingDB Entry DOI: 10.7270/Q2ZK5H08
More data for this
Ligand-Target Pair