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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor 2' and Ligand = 'BDBM50000130'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor 2


(Homo sapiens (Human))
BDBM50000130
PNG
(CHEMBL320550)
Show SMILES OC1C(O)C(NC(=O)COc2ccc(Cl)cc2Cl)OC(C1O)C(O)=O
Show InChI InChI=1S/C14H15Cl2NO8/c15-5-1-2-7(6(16)3-5)24-4-8(18)17-13-11(21)9(19)10(20)12(25-13)14(22)23/h1-3,9-13,19-21H,4H2,(H,17,18)(H,22,23)
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 25.2n/an/an/an/an/an/a



University College Dublin

Curated by ChEMBL


Assay Description
24% inhibition of FGF-2 binding to heparin-albumin by ELISA


Bioorg Med Chem Lett 12: 3287-90 (2002)


BindingDB Entry DOI: 10.7270/Q2ZP45G2
More data for this
Ligand-Target Pair