Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM339869'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM339869 (US9757364, Compound 57) Show SMILES COc1cc(OC)c(F)c(c1)N(CCCC#N)c1ccc2ncc(cc2n1)-c1cnn(C)c1 Show InChI InChI=1S/C24H23FN6O2/c1-30-15-17(14-28-30)16-10-20-19(27-13-16)6-7-23(29-20)31(9-5-4-8-26)21-11-18(32-2)12-22(33-3)24(21)25/h6-7,10-15H,4-5,9H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR1 (h) (25 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
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