Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM3428 (1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Health Science Center Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of FGFR1 (unknown origin) after 90 mins by TR-FRET assay | Bioorg Med Chem Lett 25: 1556-60 (2015) Article DOI: 10.1016/j.bmcl.2015.02.010 BindingDB Entry DOI: 10.7270/Q2NP262J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM3428 (1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Pfizer | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe... | J Med Chem 44: 1915-26 (2001) Article DOI: 10.1021/jm0004291 BindingDB Entry DOI: 10.7270/Q29K48DG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM3428 (1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research | Assay Description The kinase activity is the enzyme activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] ATP to the poly (E: Y) substrate. N... | Bioorg Med Chem Lett 7: 2415-20 (1997) Article DOI: 10.1074/jbc.M606873200 BindingDB Entry DOI: 10.7270/Q28C9TF2 | |||||||||||
More data for this Ligand-Target Pair |