Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM4615'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4615 (1,6-naphthyridine deriv. 17 | N-[2-[[(tert-Butylam...) Show SMILES COc1cc(OC)cc(c1)-c1cc2cnc(NC(C)=O)cc2nc1NC(=O)NC(C)(C)C Show InChI InChI=1S/C23H27N5O4/c1-13(29)25-20-11-19-15(12-24-20)9-18(14-7-16(31-5)10-17(8-14)32-6)21(26-19)27-22(30)28-23(2,3)4/h7-12H,1-6H3,(H,24,25,29)(H2,26,27,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 43: 4200-11 (2000) Article DOI: 10.1021/jm000161d BindingDB Entry DOI: 10.7270/Q2JW8C3G
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